2Department of Radiation Oncology, Ege University Faculty of Medicine, İzmir-Turkey DOI : 10.5505/tjo.2021.2687 OBJECTIVE
Evaluation of adjuvant therapy approach in Stage I, high and high-intermediate risk endometrioid-type uterine cancers with a survey.
METHODS
Our survey, which was designed as the Turkish Society of Radiation Oncology-Gynecological Tumors
Subgroup Study asked adjuvant therapy preference (ATP) according to different scenarios.
RESULTS
A total of 122 people participated in the survey. Myometrial invasion and grade were chosen the most
frequently evaluated prognostic factor. In patients with Stage 1A-B, Grade 1-2, lymphovascular invasion
(LVI) (+) as determined by the staging surgery (SS), the ATP was 68% for vaginal brachytherapy (VB).
In 48 (40%) participants who did not recommend SS for the patient without SS, the recommendations
were external radiotherapy (ERT)+VB in 33%. In Stage 1A, Grade 3, LVI (-) patients who had undergone
SS, the ATP was 63% for VB. For LVI (+) patients in the same group, the ATP was 43% for ERT+VB. In
39 (32.5%) participants who did not recommend SS for the patient without SS, the recommendations
were ERT+VB in 43%. In Stage 1B, Grade 3, LVI (-) patients who had undergone SS, ATP was 45% for
ERT+VB. For the LVI (+) positive patients, the ATP was 71% for ERT+VB. In 31 (26%) participants who
did not recommend SS, for the patient without SS, the recommendations were ERT+VB in 55%.
CONCLUSION
Our survey showed that ATP of participants was similar to current guidelines. They preferred adjuvant
therapy as a multi-modality treatment instead of single-modality in the presence of prognostic factors,
such as not performing SS or LVI.