TURKISH JOURNAL OF ONCOLOGY 2021 , Vol 36 , Num 3
The Importance of Apoptosis in Cancer Development and Treatment
İrem Nur GÖKBAYRAK ATAY1,Ayhan Hilal GEZER2,Elmas KASAP3
1Department of Neuroscience, Dokuz Eylül University Faculty of Health Sciences Institute, İzmir-Turkey
2Department of Medical Biology, Celal Bayar University Faculty of Medicine, Manisa-Turkey
3Department of Internal Medicine and Gastroenterology, Celal Bayar University Faculty of Medicine, Manisa-Turkey
DOI : 10.5505/tjo.2021.2574 Cancer is one of the most important causes of death in our era. Multifactorial causes are involved in the formation of cancer. The reduction of apoptosis is one of these reasons. Failure to activate apoptosis pathways can lead to resistance to the current treatment approaches of cancers. A better understanding of the molecular events that regulate apoptosis in cancers and cancer therapy form the basis of a more rational approach to the development of molecular targeted therapies in the fight against cancer. Keywords : Apoptosis; apoptosis pathways; cancer; cancer development; cancer treatment